Drug Discovery

Chemistry

Our expert chemists thoughtfully apply our resources — including a proprietary DNA-encoded library — to refine and purify the compound, perfecting the profile no matter how time-sensitive or complex the challenge.

Biophysics

See more clearly with our comprehensive biophysics platform. You will get a more meaningful, complete view of the molecule and interactions: characterization, appearance, behavior, binding.

Pharmacology and DMPK

Move closer to market with our therapeutic area expertise, in vitro assays, in vivo models and deep understanding of both disease and drug mode of action. Our custom solutions help connect preclinical efficacy with clinical success.

ADME-PK and preformulation

A rigorous suite of assays to test compound profile: in vitro ADME assays, in vivo PharmacoKinetics, as well as batch analysis and formulation design. 

Medicinal chemistry

Interdisciplinary team focused on the design, synthesis, improvement of biological activity, and the safety and pharmacokinetic properties in order to discover new drug candidates.

Chemoinformatics

Computational chemistry is a powerful tool utilizing computer modeling and simulations to explore molecular behavior and predict the properties of new compounds. By employing various computational techniques, our researchers can significantly accelerate a medicinal chemistry project and reduce timelines.

DNA-encoded libraries

DNA-encoded libraries (DELs) represent a novel and robust approach to hit identification and rapid lead generation that can provide access to a broad set of diverse chemotypes for a significantly lower cost than high-throughput screening (HTS). Currently, the number of DEL-enabled drug discovery programs continues to rise. The fully integrated NovaDEL platform, transferred from an alliance and license deal with a major pharmaceutical company, is built on the concept of capturing and tracking all experimental information as it is generated from library synthesis through affinity selection.