Biophysics

X-ray crystallography

An expert service: two decades of experience

Key aspects of Novalix know-how and capabilities:

  • Broad and diverse crystal gallery
    Kinases, nuclear receptors, phosphodiesterases, proteases, viral proteins, protein protein interaction (PPI) targets , epigenetic and membrane proteins
  • Full protein gallery list sent upon request
  • 600+ crystal structures solved for more than 130 different proteins (excluding mutants or variants)
  • Support for structure-based drug design (SBDD)
  • Monthly privileged access to SOLEIL synchrotron for data collection
  • Optimized high throughput crystallization workflow

Novalix Crystal gallery

Structure determination of targets in our gallery.
Full gallery upon request.

1-3 months.

Published structures

Reproduction of literature.

1-3 months.

De novo structure determination

Finding the optimum construct:

  • Sequence alignment with homologues
  • Secondary structure and domain preditions
  • Design of multiple constructs
  • Experimental phasing

1-3 months.