Biophysics

Protein production

Crystallographic grade custom protein synthesis

Crystallographic grade recombinant protein, suitable for biophysical techniques and biochemical assays, can be provided off-the-shelf or by customized production.

  • In silico sequence analysis and design of multiple constructs to aid solubility and crystallization
  • Prokaryotic (E. coli) and eukaryotic (insect cells and mammalian cells) production systems with codon-optimized genes
  • Quality control using native mass spectrometry and dynamic light scattering
  • Isotopic labeling

Novalix has built up expertise in difficult systems, such as nuclear hormone receptors (NHR), and has developed special protocols to produce membrane proteins.