Biophysics

Protein production

Crystallographic grade custom protein synthesis

Crystallographic grade recombinant protein, suitable for biophysical techniques and biochemical assays, can be provided off-the-shelf or by customized production.

  • in silico sequence analysis and design of multiple constructs to aid solubility and crystallization
  • Prokaryotic (E. coli) and eukaryotic (insect cells and mammalian cells) production systems with codon-optimized genes
  • Quality control using mass spectrometry, nano differential scanning fluorimetry (NanoDSF), Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) 
  • Isotopic labeling

Novalix has built up expertise in difficult systems, such as nuclear hormone receptors (NHR), and has developed special protocols to produce membrane proteins, such as GPCRs. 

Empower your research with tailor-made proteins and advanced production systems — contact us to collaborate with our experts.