Biophysics

Novalens: A better view

See more clearly with our comprehensive biophysics platform. You will get a more meaningful, complete view of the molecule and interactions: characterization, appearance, behavior, binding.

See more clearly

Novalix has assembled all the disciplines, expertise and techniques that make a world-class biophysics research partner.

Protein production

Crystallographic grade recombinant protein synthesis for biophysical techniques and biochemical assays, off-the-shelf or customized production.

Cryo-electron microscopy

Our cryo-EM facility provides leading edge technology to support and solve structure-based drug design projects (SBDD).

X-ray crystallography

Novalix offers two decades of expertise in this area, including: broad, diverse crystal gallery; full protein gallery list; 600+ crystal structures; SBDD support; monthly privileged access to SOLEIL synchrotron; optimized high throughput crystallization workflow.

Nuclear magnetic resonance (NMR)

The gold standard for fragment identification: Novalix has state-of-the-art instrumentation for screening, protein characterization and binding experiments.

Surface plasmon resonance (SPR)

Our surface plasmon resonance experts develop new methods for challenging targets or apply existing methods for routine analysis; Equilibrium constants, kinetics and screening are measured using a Biacore T200 or S200. We can support the screening of several thousands of compounds using our SPR Bruker 32 PRO system or Biacore 8K.

Mass spectrometry (MS)

The latest in both native and hydrogen-deuterium exchange (HDX) mass spectrometry for protein characterization and interaction studies, plus the Affinity Selection (AS)-MS binding assay technology for screening of large library of small molecules and hits identification.

Meet our experts

Some of the key leaders on the Novalix team in our Biophysics platform

François Debaene

Head of mass spectrometry

14 years of expertise structural mass spectrometry (10 in biopharma and CROs), HDX/Native MS/screening. 32 publications.

Céline Ronin

Head of soluble proteins

More than 15 years of experience in protein production and X-ray crystallography. Expert in structural determination of small molecule-protein complexes.

Marc Vitorino

Head of NMR

Over 15 years of experience in biotech and CROs. Applying HighField NMR in drug discovery, structural biology and analytics.

Julie Guillaume

Protein Science, Scientist

Over 17 years of experience in the pharmaceutical industry, with broad expertise in protein expression, purification and crystallization. Currently leading the Protein Science mammalian cell platform.

Novalens at work