Abigail G. Doyle et al. have developed a mild, photocatalytic method for diverse site-selective C (sp3)−H functionalisation:
- Sulfonyl)amidation, azolation, hydroxylation, esterification, etherification, and halogenation.
- Low-cost nucleophiles as coupling partners.
- A novel organic photocatalyst used: CF3-4-CzIPN.
- HAT-ORPC (oxidative radical-polar crossover) mechanism.
Publication Authors:
Madeline E. Ruos, R. Garrison Kinney, Oliver T. Ring, and Abigail G. Doyle*. J. Am. Chem. Soc. 2023, 145, 33, 18487–18496). https://doi.org/10.1021/jacs.3c04912
Published: August 11, 2023
We overcome organic synthesis challenges using this reaction and more!
Find out more about our chemistry services
