2nd NovAliX Virtual Conference
The upcoming NovAliX Conference | US Edition 2021 will take place on 9-12 March, 2021 in a fully digital setting.
All registered attendees will be able to access the event in a new format with content accessible during and after the actual conference:
- Online Sessions – attendees will access the full scientific program via a new and dedicated digital platform. Live Q&A will enable interaction with the speakers.
- Replay – following the event, the replay of the sessions will be available to all registered participants.
- A Virtual Poster Hall will allow all participants to present and discuss their latest results in a chat.
- A Virtual Exhibition will take place during the NovAliX Conference and give industry partners the opportunity to showcase products and novelties.
As this event was originally planned to take place in Boston, the online sessions will be scheduled in US-friendly time zones. The program will spread over 4 days with one session every day from 1:00 pm to 4:00 pm (EST time zone).
Program
Tuesday March 9, 2021
01:00 pm EST | 10:00 am PST | 7:00 pm CET
Opening Address by Conference Chairman
Dr Jean-Paul RENAUD
URANIA THERAPEUTICS, Ostwald, France
SESSION 1: HOT TOPIC – COVID-19
01:10 pm EST | 10:10 am PST | 7:10 pm CET
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant (OC01)
Dr Xue WANG
THERMO FISHER SCIENTIFIC, Eindhoven, The Netherlands
SESSION 2: INDUCED-PROXIMITY DRUG DISCOVERY: SELECTIVE PROTEIN DEGRADERS, PPI STABILIZERS…
01:25 pm EST | 10:25 am PST | 7:25 pm CET
Introduction by the Session Chair
01:35 pm EST | 10:35 am PST | 7:35 pm CET
The Structural Basis of Indisulam-Mediated Recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 Ligase Complex (IL01)
Dr Dirksen BUSSIERE
ELI LILLY, San Diego, United States
02:05 pm EST | 11:05 am PST | 8:05 pm CET
Exhibitor Short Presentation – NanoImaging Services: Leading the Revolution: CryoEM-Enabled Drug Discovery
02:15 pm EST | 11:15 am PST | 8:15 pm CET
Oral Communication to be selected
02:30 pm EST | 11:30 am PST | 8:30 pm CET
Exhibitor Short Presentation – Crelux, a WuXi AppTec company: Target To Hit Solutions: Drug Discovery Of Bifunctional Molecules
02:40 pm EST | 11:40 am PST | 8:40 pm CET
Targeting a Cryptic Binding Pocket by Disulfide-Induced Rupture of a Homodimeric Protein-Protein Interface (OC03)
Dr Dzung NGUYEN
PHILIPPS-UNIVERSITÄT MARBURG, Marburg, Germany
02:55 pm EST | 11:55 am PST | 8:55 pm CET
Dissecting Protein-Protein Interaction Networks (KL01)
Prof. Michelle ARKIN
UNIVERSITY OF CALIFORNIA, San Francisco, United States
03:40 pm EST | 12:40 pm PST | 9:40 pm CET
Networking
05:00 pm EST | 2:00 pm PST | 11:00 pm CET
End of the day
Wednesday March 10, 2021
12:00 pm EST | 9:00 am PST | 6:00 pm CET
Networking, Exhibiton & Posters
SESSION 3: INTEGRATIVE STRUCTURAL BIOLOGY & BIOPHYSICS
01:00 pm EST | 10:00 am PST | 7:00 pm CET
Introduction by the Session Chair
01:10 pm EST | 10:10 am PST | 7:10 pm CET
Hijacking Molecular Plasticity to Fine Tune Nuclear Receptor Signaling: Stuctural Proteomics and Precision Therapeutics (IL02)
Prof. Patrick GRIFFIN
THE SCRIPPS RESEARCH INSTITUTE, Jupiter, United States
01:40 pm EST | 10:40 am PST | 7:40 pm CET
Identification, Characterization and Conformational Assessment of STING Modulators (IL03)
Dr Daniel WYSS
MERCK, Kenilworth, United States
02:10 pm EST | 11:10 am PST | 8:10 pm CET
Exhibitor Short Presentation – NovAliX: Drug Discovery fueled with biophysics
02:20 pm EST | 11:20 am PST | 8:20 pm CET
Synergistic Use of Ligand Based NMR and Crystallography to Elucidate Small Molecules Interactions with Challenging Targets (OC04)
Dr Ariele VIACAVA FOLLIS
EMD SERONO R&D INSTITUTE INC, Stow, United States
02:35 pm EST | 11:35 am PST | 8:35 pm CET
Exhibitor Short Presentation – Wuxi Biortus Biosciences Co., Ltd.: Your Partner for Proteins and Structures
02:45 pm EST | 11:45 am PST | 8:45 pm CET
Fragment Screening Reveals a Novel Pocket in Cysteine Protease ATG4B (OC05)
Dr Troy JOHNSON
UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER, Houston, United States
03:00 pm EST | 12:00 pm PST | 9:00 pm CET
Exhibitor Short Presentation – Bruker: An Introduction to Bruker SPR Technology
03:10 pm EST | 12:10 pm PST | 9:10 pm CET
Inhibition of the Cysteine Desulfurase in the SUF Pathway of Iron-Sulfur Cluster Biogenesis Towards Development of Novel Antibacterials (OC06)
Dr Amy BONCELLA
COLORADO SCHOOL OF MINES, Golden, United States
03:25 pm EST | 12:25 pm PST | 9:25 pm CET
Networking, Exhibition & Posters
05:00 pm EST | 2:00 pm PST | 11:00 pm CET
End of the day
Thursday March 11, 2021
12:00 pm EST | 9:00 am PST | 6:00 pm CET
Networking, Exhibiton & Posters
SESSION 4: CRYO-EM IN DRUG DISCOVERY – ACCELERATING DRUG DESIGN FOR INTRACTABLE TARGETS
A full day session organized by Thermo Fisher Scientific, Platinum Sponsor of the NovAliX Conference
01:00 pm EST | 10:00 am PST | 7:00 pm CET
Introduction of the day
Session Chair
Dr Jeffrey LENGYEL
THERMO FISHER SCIENTIFIC, New York, United States
01:15 pm EST | 10:15 am PST | 7:15 pm CET
From Concept to Reality: CryoEM as an Integral Part of Drug Discovery and Development (IL04)
Dr Corey STRICKLAND
MERCK, Kenilworth, United States
01:45 pm EST | 10:45 am PST | 7:45 pm CET
Structural Characterization of Different TRPA1 Inhibitors (IL05)
Dr Lionel ROUGÉ
GENENTECH, San Francisco, United States
02:15 pm EST | 11:15 am PST | 8:15 pm CET
Improving Protein-Ligand Modeling into Cryo-EM Data and the use of those Models in Drug Discovery Efforts (IL06)
Dr Kenneth BORRELLI
SCHRÖDINGER, INC., New York, United States
02:45 pm EST | 11:45 am PST | 8:45 pm CET
Using Cryo-EM for GPCR Drug Discovery and Development (IL07)
Prof. Patrick M. SEXTON
MONASH UNIVERSITY, Parkville, Australia
03:15 pm EST | 12:15 pm PST | 9:15 pm CET
Break
Panel Discussion: Cryo-EM in Drug Discovery – Accelerating Drug Design for Intractable Targets
03:20 pm EST | 12:20 pm PST | 9:20 pm CET
Moderator
Dr Jeffrey LENGYEL
THERMO FISHER SCIENTIFIC, New York, United States
Speakers
Dr Benjamin APKER
MITEGEN, Ithaca, United States
Dr Corey STRICKLAND
MERCK, Kenilworth, United States
Dr Denis ZEYER
NOVALIX, Illkirch, France
04:05 pm EST | 1:05 pm PST | 10:05 pm CET
Networking
SESSION 5: ADVANCES IN BIOPHYSICAL TECHNIQUES: SINGLE-MOLECULES TECHNIQUES, LABEL-FREE TECHNOLOGIES, SURGACE-INMOBILIZED TECHNIQUES BEYOND SPR, ETC.
Friday March 12, 2021
Session 5: Advances in Biophysical Techniques : Single-Molecule Techniques, Label-Free Technologies, Surface-Immobilized Techniques beyond SPR, etc.
01:00 pm EST | 10:00 am PST | 7:00 pm CET
Introduction by the Session Chair
01:10 pm EST | 10:10 am PST | 7:10 pm CET
Ligand-Dependent Structural Plasticity of TrkA Kinase Studied by NMR Spectroscopy (IL08)
Dr Reto HORST
PFIZER, INC., Grotton, United States
01:40 pm EST | 10:40 am PST | 7:40 pm CET
SAR by 19F NMR: Using Protein-Observed Fluorine NMR for Targeting Protein Complexes (IL09)
Prof. William POMERANTZ
UNIVERSITY OF MINNESOTA, Minneapolis, United States
02:10 pm EST | 11:10 am PST | 8:10 pm CET
Exhibitor Short Presentation – Dynamic Biosensors: heliX® biosensor – your structure-based drug discovery tool
02:20 pm EST | 11:20 am PST | 8:20 pm CET
Real-Time Single-Molecule Detection of Drug-Protein Interactions Using a Novel DNA-Based Nanoscale Actuator (OC07)
Prof. Terence STRICK
ECOLE NORMALE SUPERIEURE, Paris, France
02:35 pm EST | 11:35 am PST | 8:35 pm CET
Exhibitor Short Presentation – MiTeGen
02:45 pm EST | 11:45 am PST | 8:45 pm CET
Development of a Microscale Thermophoresis-Based Method for Screening Inhibitors of the Methyl-Lysine Reader Protein MRG15 (OC08)
Dr Alessandra FEOLI
UNIVERSITÀ DEGLI STUDI DI SALERNO, Fisciano (Salerno), Italy
03:00 pm EST | 12:00 pm PST | 9:00 pm CET
Exhibitor Short Presentation – Biosensing Instruments
Cell-based SPR Introduction
03:10 pm EST | 12:10 pm PST | 9:10 pm CET
Focal Molography – A New Bioanalytical Tool to Eliminate Guess Work in Pharma Research (OC09)
Dr Volker GATTERDAM
LINO BIOTECH AG, Zurich, Switzerland
03:25 pm EST | 12:25 pm PST | 9:25 pm CET
Too Weak for Biophysics: Concentration-Dependent Crystallographic Soaking as Tool for Fragment Hit Prioritisation (OC10)
Ms Yuliya DUBIANOK
UNIVERSITY OF OXFORD, Oxford, United Kingdom
03:40 pm EST | 12:40 pm PST | 9:40 pm CET
Microcrystal Electron Diffraction (MicroED): Methodology and Applications (KL02)
Prof. Brent NANNENGA
ARIZONA STATE UNIVERSITY, Tempe, United States
04:25 pm EST | 1:25 pm PST | 10:25 pm CET
Closing Remarks
04:30 pm | 1:30 pm PST | 10:30 pm CET
End of the Conference
The NovAliX Conference is organized by LDO Conferences.
For more information about the event and registration, go to the conference website