At NovAliX, we are able to efficiently integrate the experience of discovery chemists with the constraints of process chemistry. Rapid implementation, new processes, removal of bottlenecks and shorter synthetic routes lead to reduced capital investment and lower cost of goods.
Our chemists design and develop safe, economic, robust, reproducible and scalable synthetic routes
- Paper Route Design
Our team delivers a detailed report that maps and evaluates possible synthetic routes to the target molecule. This report provides a guide for the next steps during the development of production processes. The creativity of our PhD chemists is complemented by the latest AI-based retrosynthetic tools.
- Route Scouting and Selection
Laboratory evaluation of the most promising routes in parallel enables rapid selection of the best route. We have established a robust process using internally developed screening platforms. In this critical process research stage, any concerns or potential problems will be identified, addressed and fully reported.
- Process Optimization
NovAliX has considerable experience of transferring processes to CDMOs, including GMP facilities.
Synthetic concepts are transformed into robust, reliable and cost-effective production processes that conform to industrial constraints. Scale-up and safety concerns are addressed. Flow chemistry is considered where appropriate.