Crystallographic grade recombinant protein, suitable for biophysical techniques and biochemical assays, can be provided off-the-shelf or by customized production.
- In silico sequence analysis and design of multiple constructs to aid solubility and crystallization
- Prokaryotic (E. coli) and eukaryotic (insect cells and mammalian cells) production systems with codon-optimized genes
- Quality control using native mass spectrometry and dynamic light scattering
- Isotopic labeling
NovAliX has built up expertise in difficult systems, such as nuclear hormone receptors (NHR), and has developed special protocols to produce membrane proteins.