Protein Production

Crystallographic grade recombinant protein, suitable for biophysical techniques and biochemical assays, can be provided off-the-shelf or by customized production.

• In silico sequence analysis and design of multiple constructs to aid solubility and crystallization
• Prokaryotic (E. coli) and eukaryotic (insect cells and mammalian cells) production systems with codon-optimized genes
• Quality control using native mass spectrometry and dynamic light scattering
• Isotopic labeling

NovAliX has built up expertise in difficult systems, such as nuclear hormone receptors (NHR), and has developed special protocols to produce membrane proteins.